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Principal/AD Biostatistician

Palo Alto, CA

Posted: 07/23/2025 Job Number: 5942

Job Description

Our client is a biopharmaceutical company with a focus on discovering new targets and developing first-in-class therapies for age-related diseases. Translating that research into first-in-class compounds, their targets are predicted also to target aging more generally, thus having the potential to extend the overall human health span. With a robust pipeline of product candidates and research, the company has the potential to truly impact quality of life for a wide range of the population.

A research and development company whose mission is to harness advanced technologies and model systems to increase our understanding of the biology that controls human aging, the goal is to use that knowledge to devise interventions that enable people to lead longer and healthier lives. Combining highly innovative technology labs, a commitment to curiosity-driven discovery science, and a robust mix of academic and industry partners, its vibrant drug-development pipeline creates an inspiring and exciting place to catalyze and enable medical breakthroughs.

They are currently seeking a Principal Biostatistician to be responsible for providing statistical data analysis expertise. This role will work with cross-functional study teams for data collection and analysis to ensure rigorous quantitative analyses in decision making for clinical studies. In addition, this individual may collaborate with internal and external partners to ensure a timely execution of study protocols and study statistical strategies to advance exciting drug candidates in clinical development programs. This role can be flexible on level according to experience. 

The company provides a scientifically stimulating and collaborative working environment, and the successful candidate will interact with scientists from a range of disciplines including basic research, computational biology, pharmacology, PKPD and biomarker experts. They are seeking a creative and innovative statistical scientist to assist project teams towards efficient strategies for data integration across multiple platforms with the ultimate goal of deriving meaningful inferences about the human condition. This is onsite role in Palo Alto, CA, and a robust relocation package is offered to those who are not currently local.

Responsibilities:

  • Provide statistical input for clinical study design
  • Develop and review statistical analysis plan for assigned studies
  • Perform ad-hoc analyses and/or simulations for assigned studies
  • Effectively collaborate with external vendors and partners
  • Contribute as a member of assigned study or project team
Position Requirements:
  • PhD in Biostatistics/Statistics or equivalent with at least 4 years relevant work experience, or MS in Biostatistics/Statistics with at least 6 years relevant work experience, in a research environment, pharmaceutical industry, or equivalent academic/applied statistics/statistical consulting experience
  • Thorough understanding of statistical principles and clinical trial methodology with the ability to practice and implement them
  • Strong technical skills, including general linear and mixed models, Bayesian statistics, multivariate models, high-dimensional data analysis, with the ability to develop innovative/creative statistical/technical solutions to complex problems
  • Ability to evaluate priorities, resolve conflicts, and adapt to changes
  • Excellent interpersonal skills and a desire to work in a team structure with individuals at all levels of the organization

The estimated base salary range for the Principal role is $198,000 - $207,000.  (Will be adjusted according to level). Actual pay will be based on a number of factors including experience and qualifications. This position is also eligible for two annual cash bonuses.

Meet Your Recruiter

Susan Devine
Director, Biometrics

Susan specializes in the recruitment of biostatisticians across all levels in the pharmaceutical, biotech, and CRO industries. Before joining Penfield in 2015, Susan spent over 15 years with Smith Hanley Associates and its parent company inVentiv Health, also recruiting in the biostatistics space. One of her specialties is helping companies to make the transition from an outsourced to an in-house model by hiring their first biostatistician. Through continual research she strives to remain current on industry trends, as well as to provide a long-term “big picture” perspective to both clients and candidates.

Susan values an ethical, proactive, and personal approach. She holds a BFA in Painting from Syracuse University. 

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